Studies > Photobiomodulation Studies > Low-level laser therapy (LLLT; 780 nm) acts differently on mRNA expression of anti- and pro-inflammatory mediators in an experimental model of collagenase-induced tendinitis in rat
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Low-level laser therapy (LLLT; 780 nm) acts differently on mRNA expression of anti- and pro-inflammatory mediators in an experimental model of collagenase-induced tendinitis in rat

Author: Pires D, Xavier M, Araujo T, Silva JA Jr, Aimbire F, Albertini R

A rat model of induced tendonitis was used to evaluate the effect of laser therapy on inflammatory signaling.   The laser group had significantly lower mRNA for IL-6, COX-2 and TGF-β than control animals in both acute and chronic phases.  Laser therapy significantly reduced mRNA TNF-α only at the chronic phase. Laser therapy is effective for the reduction of mRNA expression for pro-inflammatory mediators.

Published:  Lasers in Medical Science. 2011; 26: 85–94. doi: 10.1007/s10103-010-0811-z
Keywords:  LLLT, tendinitis, inflammatory mediators, RT-PCR, rat

About the author(s)

Pires D, Xavier M, Araujo T, Silva JA Jr, Aimbire F, Albertini R

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