PRP 101
The world of veterinary medicine continues to evolve and with it comes new treatment modalities. Platelet rich plasma (PRP) is a prime example of this evolution. For years it has been used in human medicine to help with bone grafts, heal tendon and ligament lesions and promote wound healing. It is not until recently that PRP therapy and its benefits has made its way over to veterinary medicine.
What exactly is PRP and why is it beneficial?
Platelet Rich Plasma is an autologous (self-derived) conditioned plasma that contains a high concentration of platelets. Platelets contain numerous growth factors that facilitate tissue repair and healing. These growth factors are contained in the alpha granule portion of the cell and are released from the platelet when it is activated (usually at an area of injury). A few examples of these growth factors are: Transforming Growth Factor β (TGF-β), Platelet Derived Growth Factor (PDGF), Insulin-like Growth Factor (IGF-1), Vascular Endothelial Growth Factor (VEGF), Epidermal Growth Factor (EGF) and Fibroblast Growth Factor (FGF). Roles of these growth factors range from vessel development and repair, to cellular recruitment and activation.
What can PRP be used for?
In veterinary medicine, PRP has been used for a wide range of indications including acute and chronic soft tissue injuries, osteoarthritis and even certain spinal conditions. Because PRP is obtained from the patient’s own blood, there is minimal risk and the positive effects of treatment can last for up to a year. In addition to these benefits, PRP is relatively inexpensive and can be done at patient-side in less than 30 minutes with a quality system. Stay tuned for “Stem Cell 101” where we explore stem cells and their applications in veterinary medicine.
How soon after PRP can a dog receive Nsaids?
It is generally recommended that a patient be withheld from NSAID’s 1 week prior to PRP administration and 2 weeks post-administration.