Platelet Rich Plasma – Indications For Use

“Platelet Rich Plasma- Indications For Use”

In our previous post titled “Growth Factors- What Are They and Why Are They Important?”, we took a closer look at the components that provide the benefits in Platelet Rich Plasma. Now that we have an understanding of why Platelet Rich Plasma is beneficial, it’s time to look at what conditions it can be used for.

One of the most common conditions that can be treated with Platelet Rich Plasma is osteoarthritis. Also referred to as Degenerative Joint Disease or DJD, osteoarthritis is the most common cause of lameness in dogs. It affects 1 out of 5 adult dogs and 4 out of 5 geriatric dogs (>8 years old) in North America.* Osteoarthritis is progressive and permanently deteriorates the cartilage in the joints, which can lead to painful bone-on-bone contact if left untreated. Because osteoarthritis in progressive, it is important to detect the disease in its early stages and treat it effectively to prevent further damage.

When PRP is used as a treatment for osteoarthritis, it provides several benefits to the affected joint, including:

  • Increased lubrication of joint space
  • Preservation of remaining cartilage
  • Increased production and preservation of cellular matrix (Hyaluronic Acid, Chondroitin Sulfate, Collagen, etc.)
  • Decreased inflammation (modulates inflammatory cytokines)
  • Reduction in pain

Platelet Rich Plasma can also be used to treat soft tissue injuries including ligament and tendon tears. It has been shown to accelerate healing and repair of these injuries through the gradual release of its growth factors and attraction of numerous cell types to the site of injury. Additionally, it has been shown to increase tensile strength of tendons after administration, reducing the likelihood of re-injury in the area of damage. Just as with osteoarthritis, it is important to have a definitive diagnosis confirmed by either needle scope or ultrasound.

Additionally, PRP has been shown to be beneficial in the treatment of burn wounds, open wounds, certain spinal conditions and in the preparation of bone graft material. To request more information about Platelet Rich Plasma and the Companion Regenerative Therapies System, click here.

Stay tuned for next week’s post where we will go over canine system validation and why it’s important.


*Johnston SA. Osteoarthritis: Joint anatomy, physiology, and pathobiology. Vet Clin North Am Small Anim Pract. 1997, 27: 699-723.


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