Leukocyte and Platelet Rich Plasma (L-PRP) Versus Leukocyte and Platelet Rich Fibrin (L-PRF) For Articular Cartilage Repair of the Knee: A Comparative Evaluation in an Animal Model

Published:  Iran Red Crescent Med J. 2015 Oct 28;17(10):e19594. doi: 10.5812/ircmj.19594. eCollection 2015

Authors:  Kazemi D, Fakhrjou A.

Summary:  Articular cartilage injuries of the knee are among the most debilitating injuries leading to osteoarthritis due to limited regenerative capability of cartilaginous tissue. The use of platelet concentrates containing necessary growth factors for cartilage healing has recently emerged as a new treatment method. This study investigated the efficacy of two types of different platelet concentrates were compared in the treatment of acute articular cartilage injuries of the knee in an animal model. The results of this study indicate that both L-PRP and L-PRF could be used to effectively promote the healing of articular cartilage defects of the knee.

Key words:  Articular Cartilage; Cartilage; Dogs; Knee Joint; Platelet-Rich Plasma

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